Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing

WBP2 encodes the WW domain‐binding protein 2 that acts as a transcriptional coactivator for estrogen receptor α (ESR1) and progesterone receptor (PGR). We reported that the loss of Wbp2 expression leads to progressive high‐frequency hearing loss in mouse, as well as in two deaf children, each carryi...

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Detalles Bibliográficos
Autores principales: Buniello, Annalisa, Ingham, Neil J, Lewis, Morag A, Huma, Andreea C, Martinez‐Vega, Raquel, Varela‐Nieto, Isabel, Vizcay‐Barrena, Gema, Fleck, Roland A, Houston, Oliver, Bardhan, Tanaya, Johnson, Stuart L, White, Jacqueline K, Yuan, Huijun, Marcotti, Walter, Steel, Karen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772953/
https://www.ncbi.nlm.nih.gov/pubmed/26881968
http://dx.doi.org/10.15252/emmm.201505523

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