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A non‐canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation

Centrioles are the major constituents of the animal centrosome, in which Plk4 kinase serves as a master regulator of the duplication cycle. Many eukaryotes also contain numerous peripheral particles known as centriolar satellites. While centriolar satellites aid centriole assembly and primary cilium...

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Detalles Bibliográficos
Autores principales: Hori, Akiko, Barnouin, Karin, Snijders, Ambrosius P, Toda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772974/
https://www.ncbi.nlm.nih.gov/pubmed/26755742
http://dx.doi.org/10.15252/embr.201541432