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Igf1 and Pacap rescue cerebellar granule neurons from apoptosis via a common transcriptional program

A shift of the delicate balance between apoptosis and survival-inducing signals determines the fate of neurons during the development of the central nervous system and its homeostasis throughout adulthood. Both pathways, promoting or protecting from apoptosis, trigger a transcriptional program. We c...

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Detalles Bibliográficos
Autores principales: Maino, B, D’Agata, V, Severini, C, Ciotti, MT, Calissano, P, Copani, A, Chang, Y-C, DeLisi, C, Cavallaro, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773033/
https://www.ncbi.nlm.nih.gov/pubmed/26941962
http://dx.doi.org/10.1038/cddiscovery.2015.29