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Igf1 and Pacap rescue cerebellar granule neurons from apoptosis via a common transcriptional program
A shift of the delicate balance between apoptosis and survival-inducing signals determines the fate of neurons during the development of the central nervous system and its homeostasis throughout adulthood. Both pathways, promoting or protecting from apoptosis, trigger a transcriptional program. We c...
Autores principales: | Maino, B, D’Agata, V, Severini, C, Ciotti, MT, Calissano, P, Copani, A, Chang, Y-C, DeLisi, C, Cavallaro, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773033/ https://www.ncbi.nlm.nih.gov/pubmed/26941962 http://dx.doi.org/10.1038/cddiscovery.2015.29 |
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