Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System

The methodology for site-directed editing of single nucleotides in the vertebrate genome is of considerable interest for research in biology and medicine. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 type II (Cas9) system has emerged as a simple...

Descripción completa

Detalles Bibliográficos
Autores principales: Armstrong, Gary Alan Barclay, Liao, Meijiang, You, Zhipeng, Lissouba, Alexandra, Chen, Brian Edwin, Drapeau, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773037/
https://www.ncbi.nlm.nih.gov/pubmed/26930076
http://dx.doi.org/10.1371/journal.pone.0150188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773037/
https://www.ncbi.nlm.nih.gov/pubmed/26930076
http://dx.doi.org/10.1371/journal.pone.0150188

Ejemplares similares