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Reconstructing Causal Biological Networks through Active Learning

Reverse-engineering of biological networks is a central problem in systems biology. The use of intervention data, such as gene knockouts or knockdowns, is typically used for teasing apart causal relationships among genes. Under time or resource constraints, one needs to carefully choose which interv...

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Detalles Bibliográficos
Autores principales: Cho, Hyunghoon, Berger, Bonnie, Peng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773135/
https://www.ncbi.nlm.nih.gov/pubmed/26930205
http://dx.doi.org/10.1371/journal.pone.0150611

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