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Reconstructing Causal Biological Networks through Active Learning
Reverse-engineering of biological networks is a central problem in systems biology. The use of intervention data, such as gene knockouts or knockdowns, is typically used for teasing apart causal relationships among genes. Under time or resource constraints, one needs to carefully choose which interv...
Autores principales: | Cho, Hyunghoon, Berger, Bonnie, Peng, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773135/ https://www.ncbi.nlm.nih.gov/pubmed/26930205 http://dx.doi.org/10.1371/journal.pone.0150611 |
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