Impaired Autophagy in Adult Bone Marrow CD34(+) Cells of Patients with Aplastic Anemia: Possible Pathogenic Significance

Aplastic anemia (AA) is a bone marrow failure syndrome that is caused largely by profound quantitative and qualitative defects of hematopoietic stem and progenitor cells. However, the mechanisms underlying these defects remain unclear. Under conditions of stress, autophagy acts as a protective mecha...

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Detalles Bibliográficos
Autores principales: Huang, Jinbo, Ge, Meili, Lu, Shihong, Shi, Jun, Yu, Wei, Li, Xingxin, Wang, Min, Zhang, Jizhou, Feng, Sizhou, Dong, Shuxu, Cheng, Xuelian, Zheng, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773166/
https://www.ncbi.nlm.nih.gov/pubmed/26930650
http://dx.doi.org/10.1371/journal.pone.0149586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773166/
https://www.ncbi.nlm.nih.gov/pubmed/26930650
http://dx.doi.org/10.1371/journal.pone.0149586

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