Cargando…

Impaired Autophagy in Adult Bone Marrow CD34(+) Cells of Patients with Aplastic Anemia: Possible Pathogenic Significance

Aplastic anemia (AA) is a bone marrow failure syndrome that is caused largely by profound quantitative and qualitative defects of hematopoietic stem and progenitor cells. However, the mechanisms underlying these defects remain unclear. Under conditions of stress, autophagy acts as a protective mecha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jinbo, Ge, Meili, Lu, Shihong, Shi, Jun, Yu, Wei, Li, Xingxin, Wang, Min, Zhang, Jizhou, Feng, Sizhou, Dong, Shuxu, Cheng, Xuelian, Zheng, Yizhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773166/ https://www.ncbi.nlm.nih.gov/pubmed/26930650 http://dx.doi.org/10.1371/journal.pone.0149586

Ejemplares similares

CD106 is a novel mediator of bone marrow mesenchymal stem cells via NF-κB in the bone marrow failure of acquired aplastic anemia
por: Lu, Shihong, et al.
Publicado: (2017)

Increased Bone Marrow (BM) Plasma Level of Soluble CD30 and Correlations with BM Plasma Level of Interferon (IFN)-γ, CD4/CD8 T-Cell Ratio and Disease Severity in Aplastic Anemia
por: Wu, Qingqing, et al.
Publicado: (2014)

Impaired immunosuppressive effect of bone marrow mesenchymal stem cell-derived exosomes on T cells in aplastic anemia
por: Wang, Shichong, et al.
Publicado: (2023)

Outcomes of Optimized over Standard Protocol of Rabbit Antithymocyte Globulin for Severe Aplastic Anemia: A Single-Center Experience
por: Li, Xingxin, et al.
Publicado: (2013)

Association between human leukocyte antigen and immunosuppressive treatment outcomes in Chinese patients with aplastic anemia
por: Chen, Lingyun, et al.
Publicado: (2023)

Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia
por: Dong, Peiyuan, et al.
Publicado: (2022)

Multifaceted characterization of the signatures and efficacy of mesenchymal stem/stromal cells in acquired aplastic anemia
por: Huo, Jiali, et al.
Publicado: (2020)

Levamisole Suppresses CD4(+) T-Cell Proliferation and Antigen-Presenting Cell Activation in Aplastic Anemia by Regulating the JAK/STAT and TLR Signaling Pathways
por: Wang, Jiali, et al.
Publicado: (2022)

Differential Gene Expression Profile Associated with the Abnormality of Bone Marrow Mesenchymal Stem Cells in Aplastic Anemia
por: Li, Jianping, et al.
Publicado: (2012)

Dioscin Regulating Bone Marrow Apoptosis in Aplastic Anemia
por: Zhang, Le, et al.
Publicado: (2022)

Pathogenesis of Acquired Aplastic Anemia and the Role of the Bone Marrow Microenvironment
por: Medinger, Michael, et al.
Publicado: (2018)

A hemizygous p.R204Q mutation in the ALAS2 gene underlies X-linked sideroblastic anemia in an adult Chinese Han man
por: Huang, Jinbo, et al.
Publicado: (2021)

NOTCH signaling in immune-mediated bone marrow failure of aplastic anemia
por: Minter, Lisa M
Publicado: (2013)

Enhanced Adipogenicity of Bone Marrow Mesenchymal Stem Cells in Aplastic Anemia
por: Tripathy, Naresh Kumar, et al.
Publicado: (2014)

Bone Marrow Plasma Cytokine Signature Profiles in Severe Aplastic Anemia
por: Liu, Bingnan, et al.
Publicado: (2020)

Single-Cell RNA-Seq of Bone Marrow Cells in Aplastic Anemia
por: Tonglin, Hu, et al.
Publicado: (2022)

Somatic mutations in aplastic anemia: Significance for classification, therapy, and outcome
por: Wood, Henry J., et al.
Publicado: (2019)

Aplastic Anemia in China
por: Liu, Chunyan, et al.
Publicado: (2018)

Alteration in Marrow Stromal Microenvironment and Apoptosis Mechanisms Involved in Aplastic Anemia: An Animal Model to Study the Possible Disease Pathology
por: Chatterjee, Sumanta, et al.
Publicado: (2010)

Mitochondrial DNA Aberrations of Bone Marrow Cells from Patients with Aplastic Anemia
por: Kim, Hye-Ran, et al.
Publicado: (2008)

Hypercellular bone marrow in aplastic anemia: A case report of two patients
por: Sweeney, Ryan, et al.
Publicado: (2021)

Cancers after HLA-matched related Bone Marrow Transplantation for Aplastic Anemia
por: Vo, Phuong, et al.
Publicado: (2021)

Magnetic resonance imaging of the bone marrow after bone marrow transplantation or immunosuppressive therapy in aplastic anemia.
por: Park, J. M., et al.
Publicado: (2001)

Idiopathic Aplastic Anemia: An Update
por: Solomou, Elena E.
Publicado: (2019)

Aplastic anemia in the elderly: a nationwide survey on behalf of the French Reference Center for Aplastic Anemia
por: Contejean, Adrien, et al.
Publicado: (2019)

Mesenchymal Stem Cell Benefits Observed in Bone Marrow Failure and Acquired Aplastic Anemia
por: Gonzaga, Vivian Fonseca, et al.
Publicado: (2017)

Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia
por: Kekre, Natasha, et al.
Publicado: (2017)

Aplastic Anemia as a Roadmap for Bone Marrow Failure: An Overview and a Clinical Workflow
por: Solimando, Antonio G., et al.
Publicado: (2022)

The role of androgen therapy in acquired aplastic anemia and other bone marrow failure syndromes
por: Nassani, Momen, et al.
Publicado: (2023)

P1335: REPAIR OF DYSFUNCTIONAL BONE MARROW ENDOTHELIAL CELLS ALLEVIATES APLASTIC ANEMIA
por: Tang, Shu-Qian, et al.
Publicado: (2023)

P1308: RUXOLITINIB AS GRAFT-VERSUS-HOST DISEASE PROPHYLAXIS FOR ALLOGENEIC STEM CELL TRANSPLANTATION IN APLASTIC ANEMIA PATIENTS
por: Zhang, Xiaoyu, et al.
Publicado: (2023)

Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study
por: Rogers, Zora R., et al.
Publicado: (2019)

Identification of potential pathogenic genes for severe aplastic anemia by whole‐exome sequencing
por: Zhang, Yang, et al.
Publicado: (2022)

Expression Level of IL-6 Secreted by Bone Marrow Stromal Cells in Mice with Aplastic Anemia
por: Chen, Yong Feng, et al.
Publicado: (2013)

Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia
por: Roderick, Justine E., et al.
Publicado: (2013)

Aplastic anemia: immunosuppressive therapy in 2010
por: Risitano, Antonio M., et al.
Publicado: (2011)

Osteonecrosis of the hip in patients with aplastic anemia.
por: Park, Jeongmi, et al.
Publicado: (2002)

Cephalosporin-induced recurrent aplastic anemia
por: Han, Jimin, et al.
Publicado: (2010)

Ecthyma gangrenosum associated with aplastic anemia.
por: Chun, W. H., et al.
Publicado: (1996)

Aplastic anemia, membranous nephropathy and mercury
por: Rooney, J.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_rpgd3brgjtf1i8hut9kh44vj6j