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A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus

OBJECTIVE: Evidence suggests that chronic subclinical inflammation plays an important role in the pathogenesis of type 2 diabetes (T2DM). Circulating levels of interleukin (IL)-18 appear to be associated with a number of micro- and macrovascular comorbidities of obesity and T2DM. This study was desi...

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Detalles Bibliográficos
Autores principales: McKie, Elizabeth A., Reid, Juliet L., Mistry, Prafull C., DeWall, Stephen L., Abberley, Lee, Ambery, Philip D., Gil-Extremera, Blas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773233/
https://www.ncbi.nlm.nih.gov/pubmed/26930607
http://dx.doi.org/10.1371/journal.pone.0150018