Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function

It is generally accepted that ATP regulates mitochondrial function through the AMPK signaling pathway. However, the AMPK-independent pathway remains largely unknown. In this study, we investigated ATP surplus in the negative regulation of mitochondrial function with a focus on pyruvate dehydrogenase...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Zhao, Zhiyun, Ke, Bilun, Wan, Lin, Wang, Hui, Ye, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773252/
https://www.ncbi.nlm.nih.gov/pubmed/26930489
http://dx.doi.org/10.1371/journal.pone.0150454

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