Cargando…

Dynamic Compression Effects on Immature Nucleus Pulposus: a Study Using a Novel Intelligent and Mechanically Active Bioreactor

Background: Previous cell culture and animal in vivo studies indicate the obvious effects of mechanical compression on disc cell biology. However, the effects of dynamic compression magnitude, frequency and duration on the immature nucleus pulposus (NP) from an organ-cultured disc are not well under...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Pei, Gan, Yibo, Wang, Haoming, Zhang, Chengmin, Wang, Liyuan, Xu, Yuan, Song, Lei, Li, Songtao, Li, Sukai, Ou, Yangbin, Zhou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773287/ https://www.ncbi.nlm.nih.gov/pubmed/26941583 http://dx.doi.org/10.7150/ijms.13747

Ejemplares similares

Surgical removal and controlled trypsinization of the outer annulus fibrosus improves the bioactivity of the nucleus pulposus in a disc bioreactor culture
por: Li, Pei, et al.
Publicado: (2016)

A Controlled Release Codelivery System of MSCs Encapsulated in Dextran/Gelatin Hydrogel with TGF-β3-Loaded Nanoparticles for Nucleus Pulposus Regeneration
por: Gan, Yibo, et al.
Publicado: (2016)

Long-term load duration induces N-cadherin down-regulation and loss of cell phenotype of nucleus pulposus cells in a disc bioreactor culture
por: Li, Pei, et al.
Publicado: (2017)

The inflammatory cytokine TNF-α promotes the premature senescence of rat nucleus pulposus cells via the PI3K/Akt signaling pathway
por: Li, Pei, et al.
Publicado: (2017)

Low Magnitude of Compression Enhances Biosynthesis of Mesenchymal Stem Cells towards Nucleus Pulposus Cells via the TRPV4-Dependent Pathway
por: Gan, Yibo, et al.
Publicado: (2018)

17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway
por: Li, Pei, et al.
Publicado: (2017)

High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway
por: Li, Pei, et al.
Publicado: (2017)

Deficiency of MIF Accentuates Overloaded Compression-Induced Nucleus Pulposus Cell Oxidative Damage via Depressing Mitophagy
por: Wang, Yiyang, et al.
Publicado: (2021)

SIRT1 Attenuates Apoptosis of Nucleus Pulposus Cells by Targeting Interactions between LC3B and Fas under High-Magnitude Compression
por: Zhuo, Yunyun, et al.
Publicado: (2021)

SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy
por: Wang, Yiyang, et al.
Publicado: (2020)

Cyclic Tensile Strain Induces Tenogenic Differentiation of Tendon-Derived Stem Cells in Bioreactor Culture
por: Xu, Yuan, et al.
Publicado: (2015)

The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells
por: Ke, Wencan, et al.
Publicado: (2021)

Extracellular Matrix Ligand and Stiffness Modulate Immature Nucleus Pulposus Cell-Cell Interactions
por: Gilchrist, Christopher L., et al.
Publicado: (2011)

N-cadherin attenuates nucleus pulposus cell senescence under high-magnitude compression
por: Niu, Ming, et al.
Publicado: (2018)

Role of p38–MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture
por: Pang, Lianglong, et al.
Publicado: (2017)

Reduction in nerve root compression by the nucleus pulposus after Feng's Spinal Manipulation☆
por: Feng, Yu, et al.
Publicado: (2013)

Effect of Compression Loading on Human Nucleus Pulposus-Derived Mesenchymal Stem Cells
por: Liang, Hang, et al.
Publicado: (2018)

Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction
por: Wang, Yiyang, et al.
Publicado: (2022)

Role of the ERK1/2 Signaling Pathway in Osteogenesis of Rat Tendon-Derived Stem Cells in Normoxic and Hypoxic Cultures
por: Li, Pei, et al.
Publicado: (2016)

Inducing Angiogenesis in the Nucleus Pulposus
por: Damle, Sheela R., et al.
Publicado: (2023)

Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell‐Derived Exosomes on the Senescence of Nucleus Pulposus Cells
por: Chen, Chang‐chun, et al.
Publicado: (2020)

Static compression down-regulates N-cadherin expression and facilitates loss of cell phenotype of nucleus pulposus cells in a disc perfusion culture
por: Zhou, Haibo, et al.
Publicado: (2018)

Compression‐induced senescence of nucleus pulposus cells by promoting mitophagy activation via the PINK1/PARKIN pathway
por: Huang, Donghua, et al.
Publicado: (2020)

Pioglitazone Protects Compression-Mediated Apoptosis in Nucleus Pulposus Mesenchymal Stem Cells by Suppressing Oxidative Stress
por: Hu, Yiqiang, et al.
Publicado: (2019)

The response of nucleus pulposus cell senescence to static and dynamic compressions in a disc organ culture
por: Shi, Jianmin, et al.
Publicado: (2018)

Functional compressive mechanics and tissue biocompatibility of an injectable SF/PU hydrogel for nucleus pulposus replacement
por: Hu, Jingen, et al.
Publicado: (2017)

Predictors of urinary or fecal incontinence in dogs with thoracolumbar acute non‐compressive nucleus pulposus extrusion
por: Mari, Lorenzo, et al.
Publicado: (2019)

Spatially defined single-cell transcriptional profiling characterizes diverse chondrocyte subtypes and nucleus pulposus progenitors in human intervertebral discs
por: Gan, Yibo, et al.
Publicado: (2021)

The influence of L4–S1 Dynesys® dynamic stabilization versus fusion on lumbar motion and its relationship with lumbar degeneration: a retrospective study
por: Zhang, Chengmin, et al.
Publicado: (2017)

Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells
por: Liu, Ziming, et al.
Publicado: (2019)

Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy
por: Li, Gaocai, et al.
Publicado: (2020)

Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells
por: Lian, Chengjie, et al.
Publicado: (2017)

Nucleus Pulposus Cell Conditioned Medium Promotes Mesenchymal Stem Cell Differentiation into Nucleus Pulposus-Like Cells under Hypoxic Conditions
por: Sinkemani, Arjun, et al.
Publicado: (2020)

Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration
por: Xu, Meng, et al.
Publicado: (2022)

Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence
por: Li, Xiao-Chuan, et al.
Publicado: (2018)

Exosomes Derived from Bone Mesenchymal Stem Cells Alleviate Compression-Induced Nucleus Pulposus Cell Apoptosis by Inhibiting Oxidative Stress
por: Hu, Yiqiang, et al.
Publicado: (2021)

Natural Products of Pharmacology and Mechanisms in Nucleus Pulposus Cells and Intervertebral Disc Degeneration
por: Chen, Hai-Wei, et al.
Publicado: (2021)

The enigma that is the nucleus pulposus cell: the search goes on
por: Erwin, W Mark
Publicado: (2010)

Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration
por: Krouwels, Anita, et al.
Publicado: (2020)

Cell sources proposed for nucleus pulposus regeneration
por: Williams, Rebecca J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_aptatgflj7earfu78bb2e0j6o7