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Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles
In a clinical setting, where multiple administrations of the therapeutic agent are usually required to improve the therapeutic outcome, it is crucial to assess the immunogenicity of the administered nanoparticles. In this data work, we investigated the safety profile of the repeated intravenous admi...
Autores principales: | Conceição, Mariana, Mendonça, Liliana, Nóbrega, Clévio, Gomes, Célia, Costa, Pedro, Hirai, Hirokazu, Moreira, João Nuno, Lima, Maria C., Manjunath, N., de Almeida, Luís Pereira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773411/ https://www.ncbi.nlm.nih.gov/pubmed/26958628 http://dx.doi.org/10.1016/j.dib.2016.01.017 |
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