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BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation

While BTG2 plays an important role in cellular differentiation and cancer, its precise molecular function remains unclear. BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. Our previous experiments revealed that expression of BTG2 promoted mRNA poly...

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Detalles Bibliográficos
Autores principales:	Stupfler, Benjamin, Birck, Catherine, Séraphin, Bertrand, Mauxion, Fabienne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773420/ https://www.ncbi.nlm.nih.gov/pubmed/26912148 http://dx.doi.org/10.1038/ncomms10811

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