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Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair

Oxidative stress is a very frequent source of DNA damage. Many cellular DNA polymerases (Pols) can incorporate ribonucleotides (rNMPs) during DNA synthesis. However, whether oxidative stress-triggered DNA repair synthesis contributes to genomic rNMPs incorporation is so far not fully understood. Hum...

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Detalles Bibliográficos
Autores principales:	Crespan, Emmanuele, Furrer, Antonia, Rösinger, Marcel, Bertoletti, Federica, Mentegari, Elisa, Chiapparini, Giulia, Imhof, Ralph, Ziegler, Nathalie, Sturla, Shana J., Hübscher, Ulrich, van Loon, Barbara, Maga, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773436/ https://www.ncbi.nlm.nih.gov/pubmed/26917111 http://dx.doi.org/10.1038/ncomms10805

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