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Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration

We report the methodology for the chronic delivery of an excitotoxin to the mouse spinal cord via surgically implanted osmotic mini-pumps. Previous studies have investigated the effect of chronic application of excitotoxins in the rat, however there has been little translation of this model to the m...

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Detalles Bibliográficos
Autores principales: Blizzard, Catherine A., Lee, K. M., Dickson, Tracey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773442/
https://www.ncbi.nlm.nih.gov/pubmed/26973454
http://dx.doi.org/10.3389/fnins.2016.00076

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