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Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus

Regulatory T-cell (Treg) selection in the thymus is essential to prevent autoimmune diseases. Although important rules for Treg selection have been established, there is controversy regarding the degree of self-reactivity displayed by T-cell receptors expressed by Treg cells. In this study we have d...

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Detalles Bibliográficos
Autores principales:	Lin, Jiqiang, Yang, Lu, Silva, Hernandez Moura, Trzeciak, Alissa, Choi, Yongwon, Schwab, Susan R., Dustin, Michael L., Lafaille, Juan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773449/ https://www.ncbi.nlm.nih.gov/pubmed/26923114 http://dx.doi.org/10.1038/ncomms10562

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