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Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

Malignant gliomas constitute one of the most significant areas of unmet medical need, owing to the invariable failure of surgical eradication and their marked molecular heterogeneity. Accumulating evidence has revealed a critical contribution by the Polycomb axis of epigenetic repression. However, a...

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Detalles Bibliográficos
Autores principales: Signaroldi, Elena, Laise, Pasquale, Cristofanon, Silvia, Brancaccio, Arianna, Reisoli, Elisa, Atashpaz, Sina, Terreni, Maria Rosa, Doglioni, Claudio, Pruneri, Giancarlo, Malatesta, Paolo, Testa, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773478/
https://www.ncbi.nlm.nih.gov/pubmed/26923714
http://dx.doi.org/10.1038/ncomms10753