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MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis

Lymphangiogensis is involved in various pathological conditions, such as arthritis and cancer metastasis. Although many factors have been identified to stimulate lymphatic vessel growth, little is known about lymphangiogenesis inhibitors. Here we report that membrane type 1-matrix metalloproteinase...

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Detalles Bibliográficos
Autores principales:	Wong, Hoi Leong Xavier, Jin, Guoxiang, Cao, Renhai, Zhang, Shuo, Cao, Yihai, Zhou, Zhongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773521/ https://www.ncbi.nlm.nih.gov/pubmed/26926389 http://dx.doi.org/10.1038/ncomms10824

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