Implementation of new approaches for generating conventional reassortants for live attenuated influenza vaccine based on Russian master donor viruses

Cold-adapted influenza strains A/Leningrad/134/17/57 (H2N2) and B/USSR/60/69, originally developed in Russia, have been reliable master donors of attenuation for preparing live attenuated influenza vaccines (LAIV). The classical strategy for generating LAIV reassortants is robust, but has some disad...

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Detalles Bibliográficos
Autores principales: Shcherbik, Svetlana, Pearce, Nicholas, Kiseleva, Irina, Larionova, Natalie, Rudenko, Larisa, Xu, Xiyan, Wentworth, David E., Bousse, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773654/
https://www.ncbi.nlm.nih.gov/pubmed/26519883
http://dx.doi.org/10.1016/j.jviromet.2015.10.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773654/
https://www.ncbi.nlm.nih.gov/pubmed/26519883
http://dx.doi.org/10.1016/j.jviromet.2015.10.009

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