Facile construction of a highly sensitive DNA biosensor by in-situ assembly of electro-active tags on hairpin-structured probe fragment

An ultrasensitive DNA biosensor has been developed through in-situ labeling of electroactive melamine-Cu(2+) complex (Mel-Cu(2+)) on the end of hairpin-like probe using gold nanoparticles (AuNPs) as the signal amplification platform. The 3′-thiolated hairpin-like probe was first immobilized to the g...

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Detalles Bibliográficos
Autores principales: Wang, Qingxiang, Gao, Feng, Ni, Jiancong, Liao, Xiaolei, Zhang, Xuan, Lin, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773755/
https://www.ncbi.nlm.nih.gov/pubmed/26931160
http://dx.doi.org/10.1038/srep22441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773755/
https://www.ncbi.nlm.nih.gov/pubmed/26931160
http://dx.doi.org/10.1038/srep22441

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