Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death

Sestrin2 is a member of a family of stress responsive proteins, which controls cell viability via antioxidant activity and regulation of the mammalian target of rapamycin protein kinase (mTOR). Sestrin2 is induced by different stress insults, which diminish ATP production and induce energetic stress...

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Detalles Bibliográficos
Autores principales: Ding, Boxiao, Parmigiani, Anita, Divakaruni, Ajit S., Archer, Kellie, Murphy, Anne N., Budanov, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773760/
https://www.ncbi.nlm.nih.gov/pubmed/26932729
http://dx.doi.org/10.1038/srep22538

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