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Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation
Background—To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods—GH was administered (mg/day) at doses of 0.5 over thr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773770/ https://www.ncbi.nlm.nih.gov/pubmed/26821051 http://dx.doi.org/10.3390/jcm5020014 |
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author | Devesa, Jesús Lema, Hortensia Zas, Eva Munín, Borja Taboada, Pilar Devesa, Pablo |
author_facet | Devesa, Jesús Lema, Hortensia Zas, Eva Munín, Borja Taboada, Pilar Devesa, Pablo |
author_sort | Devesa, Jesús |
collection | PubMed |
description | Background—To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods—GH was administered (mg/day) at doses of 0.5 over three months followed by 0.9, every two weeks over three months, and then alternating 1.2 three days/week and 0.3 two days/week. Neurorehabilitation consisted of daily sessions of neurostimulation, speech therapy, occupational therapy and auditive stimulation. Treatment lasted nine months. Results—Scores obtained in all the areas treated showed that, at discharge, the patient clearly increased her cognitive abilities, memory and language competence index; her intelligence quotient score increased from 51 to 80, and the index of functional independence measure reached a value of 120 over 126 (maximal value). Conclusions—This case suggests that GH administration may play a role in improving cognitive deficits during neurorehabilitation in children with brain damage suffered during delivery. This agrees with the known effects of GH on cognition. |
format | Online Article Text |
id | pubmed-4773770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-47737702016-03-03 Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation Devesa, Jesús Lema, Hortensia Zas, Eva Munín, Borja Taboada, Pilar Devesa, Pablo J Clin Med Case Report Background—To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods—GH was administered (mg/day) at doses of 0.5 over three months followed by 0.9, every two weeks over three months, and then alternating 1.2 three days/week and 0.3 two days/week. Neurorehabilitation consisted of daily sessions of neurostimulation, speech therapy, occupational therapy and auditive stimulation. Treatment lasted nine months. Results—Scores obtained in all the areas treated showed that, at discharge, the patient clearly increased her cognitive abilities, memory and language competence index; her intelligence quotient score increased from 51 to 80, and the index of functional independence measure reached a value of 120 over 126 (maximal value). Conclusions—This case suggests that GH administration may play a role in improving cognitive deficits during neurorehabilitation in children with brain damage suffered during delivery. This agrees with the known effects of GH on cognition. MDPI 2016-01-26 /pmc/articles/PMC4773770/ /pubmed/26821051 http://dx.doi.org/10.3390/jcm5020014 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Devesa, Jesús Lema, Hortensia Zas, Eva Munín, Borja Taboada, Pilar Devesa, Pablo Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title | Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_full | Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_fullStr | Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_full_unstemmed | Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_short | Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_sort | learning and memory recoveries in a young girl treated with growth hormone and neurorehabilitation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773770/ https://www.ncbi.nlm.nih.gov/pubmed/26821051 http://dx.doi.org/10.3390/jcm5020014 |
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