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Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection.

TNF is crucial for controlling Mycobacterium tuberculosis infection and understanding how will help immunomodulating the host response. Here we assessed the contribution of TNFR1 pathway from innate myeloid versus T cells. We first established the prominent role of TNFR1 in haematopoietic cells for...

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Detalles Bibliográficos
Autores principales: Segueni, Noria, Benmerzoug, Sulayman, Rose, Stéphanie, Gauthier, Amandine, Bourigault, Marie-Laure, Reverchon, Flora, Philippeau, Amandine, Erard, François, Le Bert, Marc, Bouscayrol, Hélène, Wachter, Thierry, Garcia, Irène, Kollias, George, Jacobs, Muazzam, Ryffel, Bernhard, Quesniaux, Valerie F.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773807/
https://www.ncbi.nlm.nih.gov/pubmed/26931771
http://dx.doi.org/10.1038/srep22454