Cargando…

Caveolin interaction governs Kv1.3 lipid raft targeting

The spatial localization of ion channels at the cell surface is crucial for their functional role. Many channels localize in lipid raft microdomains, which are enriched in cholesterol and sphingolipids. Caveolae, specific lipid rafts which concentrate caveolins, harbor signaling molecules and their...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérez-Verdaguer, Mireia, Capera, Jesusa, Martínez-Mármol, Ramón, Camps, Marta, Comes, Núria, Tamkun, Michael M., Felipe, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773814/
https://www.ncbi.nlm.nih.gov/pubmed/26931497
http://dx.doi.org/10.1038/srep22453