A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

The histone deacetylases HDAC1 and HDAC2 are crucial regulators of chromatin structure and gene expression, thereby controlling important developmental processes. In the mouse brain, HDAC1 and HDAC2 exhibit different developmental stage- and lineage-specific expression patterns. To examine the indiv...

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Detalles Bibliográficos
Autores principales: Hagelkruys, Astrid, Lagger, Sabine, Krahmer, Julia, Leopoldi, Alexandra, Artaker, Matthias, Pusch, Oliver, Zezula, Jürgen, Weissmann, Simon, Xie, Yunli, Schöfer, Christian, Schlederer, Michaela, Brosch, Gerald, Matthias, Patrick, Selfridge, Jim, Lassmann, Hans, Knoblich, Jürgen A., Seiser, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773893/
https://www.ncbi.nlm.nih.gov/pubmed/24449838
http://dx.doi.org/10.1242/dev.100487

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