Genetic association analyses highlight biological pathways underlying mitral valve prolapse

Non-syndromic mitral valve prolapse (MVP) is a common degenerative cardiac valvulopathy of unknown aetiology that predisposes to mitral regurgitation, heart failure and sudden death(1). Previous family and pathophysiological studies suggest a complex pattern of inheritance(2–5). We performed a meta-...

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Detalles Bibliográficos
Autores principales: Dina, Christian, Bouatia-Naji, Nabila, Tucker, Nathan, Delling, Francesca N., Toomer, Katelynn, Durst, Ronen, Perrocheau, Maelle, Fernandez-Friera, Leticia, Solis, Jorge, Le Tourneau, Thierry, Chen, Ming-Huei, Probst, Vincent, Bosse, Yohan, Pibarot, Philippe, Zelenika, Diana, Lathrop, Mark, Hercberg, Serge, Roussel, Ronan, Benjamin, Emelia J., Bonnet, Fabrice, Su Hao, LO, Dolmatova, Elena, Simonet, Floriane, Lecointe, Simon, Kyndt, Florence, Redon, Richard, Le Marec, Hervé, Froguel, Philippe, Ellinor, Patrick T., Vasan, Ramachandran S., Bruneval, Patrick, Norris, Russell A., Milan, David J., Slaugenhaupt, Susan A., Levine, Robert A., Schott, Jean-Jacques, Hagege, Albert A., Jeunemaitre, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773907/
https://www.ncbi.nlm.nih.gov/pubmed/26301497
http://dx.doi.org/10.1038/ng.3383

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