Genomic approaches for understanding dengue: insights from the virus, vector, and host

The incidence and geographic range of dengue have increased dramatically in recent decades. Climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. At the same time,...

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Autores principales: Sim, Shuzhen, Hibberd, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774013/
https://www.ncbi.nlm.nih.gov/pubmed/26931545
http://dx.doi.org/10.1186/s13059-016-0907-2
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author Sim, Shuzhen
Hibberd, Martin L.
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Hibberd, Martin L.
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description The incidence and geographic range of dengue have increased dramatically in recent decades. Climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. At the same time, significant advances in genomics approaches have provided insights into host–pathogen interactions, immunogenetics, and viral evolution in both humans and mosquitoes. Here, we review these advances and the innovative treatment and control strategies that they are inspiring.
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spelling pubmed-47740132016-03-03 Genomic approaches for understanding dengue: insights from the virus, vector, and host Sim, Shuzhen Hibberd, Martin L. Genome Biol Review The incidence and geographic range of dengue have increased dramatically in recent decades. Climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. At the same time, significant advances in genomics approaches have provided insights into host–pathogen interactions, immunogenetics, and viral evolution in both humans and mosquitoes. Here, we review these advances and the innovative treatment and control strategies that they are inspiring. BioMed Central 2016-03-02 /pmc/articles/PMC4774013/ /pubmed/26931545 http://dx.doi.org/10.1186/s13059-016-0907-2 Text en © Sim and Hibberd. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Sim, Shuzhen
Hibberd, Martin L.
Genomic approaches for understanding dengue: insights from the virus, vector, and host
title Genomic approaches for understanding dengue: insights from the virus, vector, and host
title_full Genomic approaches for understanding dengue: insights from the virus, vector, and host
title_fullStr Genomic approaches for understanding dengue: insights from the virus, vector, and host
title_full_unstemmed Genomic approaches for understanding dengue: insights from the virus, vector, and host
title_short Genomic approaches for understanding dengue: insights from the virus, vector, and host
title_sort genomic approaches for understanding dengue: insights from the virus, vector, and host
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774013/
https://www.ncbi.nlm.nih.gov/pubmed/26931545
http://dx.doi.org/10.1186/s13059-016-0907-2
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