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c-MYB is a transcriptional regulator of ESPL1/Separase in BCR-ABL-positive chronic myeloid leukemia

BACKGROUND: Genomic instability and clonal evolution are hallmarks of progressing chronic myeloid leukemia (CML). Recently, we have shown that clonal evolution and blast crisis correlate with altered expression and activity of Separase, a cysteine endopeptidase that is a mitotic key player in chromo...

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Detalles Bibliográficos
Autores principales:	Prinzhorn, Wiltrud, Stehle, Michael, Kleiner, Helga, Ruppenthal, Sabrina, Müller, Martin C., Hofmann, Wolf-Karsten, Fabarius, Alice, Seifarth, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774018/ https://www.ncbi.nlm.nih.gov/pubmed/26937281 http://dx.doi.org/10.1186/s40364-016-0059-2

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