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The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion
BACKGROUND: The immunity-related GTPases (IRGs) constitute a powerful cell-autonomous resistance system against several intracellular pathogens. Irga6 is a dynamin-like protein that oligomerizes at the parasitophorous vacuolar membrane (PVM) of Toxoplasma gondii leading to its vesiculation. Based on...
Autores principales: | Schulte, Kathrin, Pawlowski, Nikolaus, Faelber, Katja, Fröhlich, Chris, Howard, Jonathan, Daumke, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774019/ https://www.ncbi.nlm.nih.gov/pubmed/26934976 http://dx.doi.org/10.1186/s12915-016-0236-7 |
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