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HIV-tat alters Connexin43 expression and trafficking in human astrocytes: role in NeuroAIDS

BACKGROUND: HIV-associated neurocognitive disorders (HAND) are a major complication in at least half of the infected population despite effective antiretroviral treatment and immune reconstitution. HIV-associated CNS damage is not correlated with active viral replication but instead is associated wi...

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Detalles Bibliográficos
Autores principales: Berman, Joan W., Carvallo, Loreto, Buckner, Clarisa M., Luers, Aimée, Prevedel, Lisa, Bennett, Michael V., Eugenin, Eliseo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774036/
https://www.ncbi.nlm.nih.gov/pubmed/26934876
http://dx.doi.org/10.1186/s12974-016-0510-1