DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid

BACKGROUND: Diabetes therapy that not only lowers glucose levels but also lengthens life spans is required. We previously demonstrated that DPP-4 inhibition ameliorated β cell apoptosis and adipose tissue inflammation in β cell-specific glucokinase haploinsufficient mice fed a diet containing a comb...

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Detalles Bibliográficos
Autores principales: Shirakawa, Jun, Okuyama, Tomoko, Kyohara, Mayu, Yoshida, Eiko, Togashi, Yu, Tajima, Kazuki, Yamazaki, Shunsuke, Kaji, Mitsuyo, Koganei, Megumi, Sasaki, Hajime, Terauchi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774120/
https://www.ncbi.nlm.nih.gov/pubmed/26937254
http://dx.doi.org/10.1186/s13098-016-0138-4

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