Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance

BACKGROUND: The nuclear orphan receptor Nur77 (NR4A1, TR3, or NGFI-B) has been shown to modulate the inflammatory response of macrophages. To further elucidate the role of Nur77 in macrophage physiology, we compared the transcriptome of bone marrow-derived macrophages (BMM) from wild-type (WT) and N...

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Detalles Bibliográficos
Autores principales: Hamers, Anouk A. J., Argmann, Carmen, Moerland, Perry D., Koenis, Duco S., Marinković, Goran, Sokolović, Milka, de Vos, Alex F., de Vries, Carlie J. M., van Tiel, Claudia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774191/
https://www.ncbi.nlm.nih.gov/pubmed/26932821
http://dx.doi.org/10.1186/s12864-016-2469-9

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