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Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis
OBJECTIVE: Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus plac...
Autores principales: | Komori, Mika, Lin, Yen Chih, Cortese, Irene, Blake, Andrew, Ohayon, Joan, Cherup, Jamie, Maric, Dragan, Kosa, Peter, Wu, Tianxia, Bielekova, Bibiana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774261/ https://www.ncbi.nlm.nih.gov/pubmed/27042677 http://dx.doi.org/10.1002/acn3.293 |
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