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PKM2 and cancer: The function of PKM2 beyond glycolysis
Metabolic reprogramming is a hallmark of cancer cells and is used by cancer cells for growth and survival. Pyruvate kinase muscle isozyme M2 (PKM2) is a limiting glycolytic enzyme that catalyzes the final step in glycolysis, which is key in tumor metabolism and growth. The present review discusses t...
Autores principales: | DONG, GAOCHAO, MAO, QIXING, XIA, WENJIE, XU, YOUTAO, WANG, JIE, XU, LIN, JIANG, FENG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774429/ https://www.ncbi.nlm.nih.gov/pubmed/26998110 http://dx.doi.org/10.3892/ol.2016.4168 |
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