Cargando…

Short hairpin RNA silencing of TGF-βRII and FZD-7 synergistically suppresses proliferation and metastasis of hepatocellular carcinoma cells

Transforming growth factor-β (TGF-β) is a multifunctional regulator of cell growth, apoptosis, differentiation and migration. The Wnt/β-catenin signaling pathway has been implicated in a wide spectrum of diseases, including numerous cancers and degenerative disease. The aim of the present study was...

Descripción completa

Detalles Bibliográficos
Autores principales:	CHEN, CONG, XUE, YUYANG, ZHANG, DEJUN, XU, WEI, XU, HAO, YAO, HONG, PEI, DONGSHENG, GU, YUMING
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774445/ https://www.ncbi.nlm.nih.gov/pubmed/26998118 http://dx.doi.org/10.3892/ol.2016.4208

Ejemplares similares

Gene Silencing of TGFβRII Can Inhibit Glioblastoma Cell Growth
por: Aval, Farzane Ordoni, et al.
Publicado: (2018)

Mutation of TGFβ-RII eliminates NSAID cancer chemoprevention
por: Martín-López, Juana, et al.
Publicado: (2017)

LINC00942 Promotes Tumor Proliferation and Metastasis in Lung Adenocarcinoma via FZD1 Upregulation
por: Wang, Ronghua, et al.
Publicado: (2021)

Drug-inducible synergistic gene silencing with multiple small hairpin RNA molecules for gene function study in animal model
por: Ying, Ming, et al.
Publicado: (2014)

PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells
por: Gong, Haixia, et al.
Publicado: (2016)

Molecular characterization and expression of TGFβRI and TGFβRII and its association with litter size in Tibetan sheep
por: Zhang, Junxia, et al.
Publicado: (2023)

FZD10 Carried by Exosomes Sustains Cancer Cell Proliferation
por: Scavo, Maria Principia, et al.
Publicado: (2019)

Short hairpin RNA of frizzled-2 suppresses the proliferation of hepatocellular carcinoma cells
por: TOMIZAWA, MINORU, et al.
Publicado: (2014)

Expression pattern, prognostic value and potential microRNA silencing of FZD8 in breast cancer
por: Al-Zahrani, Maryam H., et al.
Publicado: (2023)

Overexpression of FZD7 promotes glioma cell proliferation by upregulating TAZ
por: Qiu, Xia, et al.
Publicado: (2016)

FZD5 contributes to TNBC proliferation, DNA damage repair and stemness
por: Sun, Yu, et al.
Publicado: (2020)

Selective gene silencing by viral delivery of short hairpin RNA
por: Sliva, Katja, et al.
Publicado: (2010)

CAPN5 gene silencing by short hairpin RNA interference
por: Nelson, Nnamdi G, et al.
Publicado: (2014)

MicroRNA‐30c suppresses the pro‐fibrogenic effects of cardiac fibroblasts induced by TGF‐β1 and prevents atrial fibrosis by targeting TGFβRII
por: Xu, Juan, et al.
Publicado: (2018)

TGF-βRII regulates glucose metabolism in oral cancer-associated fibroblasts via promoting PKM2 nuclear translocation
por: Wu, Fanglong, et al.
Publicado: (2022)

Clinical Implications of TβRII Expression in Breast Cancer
por: Gao, Ningning, et al.
Publicado: (2015)

FZD7 accelerates hepatic metastases in pancreatic cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling
por: Zhang, Zhongbo, et al.
Publicado: (2022)

TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro
por: Mao, Zhaomin, et al.
Publicado: (2017)

The miR-130a-3p/TGF-βRII Axis Participates in Inhibiting the Differentiation of Fibroblasts Induced by TGF-β1
por: Liu, Yanhong, et al.
Publicado: (2021)

TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanism
por: Varadaraj, Archana, et al.
Publicado: (2017)

Soluble CD23 (Fc epsilon RII) and interleukin 1 synergistically induce early human thymocyte maturation
Publicado: (1990)

FZD2 regulates cell proliferation and invasion in tongue squamous cell carcinoma
por: Huang, Li, et al.
Publicado: (2019)

Hydroxysafflor Yellow A Suppresses MRC-5 Cell Activation Induced by TGF-β1 by Blocking TGF-β1 Binding to TβRII
por: Pan, Ruiyan, et al.
Publicado: (2017)

Analysis of hairpin RNA transgene-induced gene silencing in Fusarium oxysporum
por: Schumann, Ulrike, et al.
Publicado: (2013)

Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3
por: Yao, Jianning, et al.
Publicado: (2018)

Immunohistochemical Expression of TGF-Β1, SMAD4, SMAD7, TGFβRII and CD68-Positive TAM Densities in Papillary Thyroid Cancer
por: Ivanova, Koni, et al.
Publicado: (2018)

MiR-199a Regulates Cell Proliferation and Survival by Targeting FZD7
por: Song, Jiugang, et al.
Publicado: (2014)

Silencing of keratin 17 by lentivirus-mediated short hairpin RNA inhibits the proliferation of PANC-1 human pancreatic cancer cells
por: Chen, Peng, et al.
Publicado: (2020)

Protein kinase C βII and TGFβRII in ω-3 fatty acid–mediated inhibition of colon carcinogenesis
por: Murray, Nicole R., et al.
Publicado: (2002)

Chemical induction of hairpin RNAi molecules to silence vital genes in plant roots
por: Liu, Siming, et al.
Publicado: (2016)

PolyPurine Reverse Hoogsteen Hairpins Work as RNA Species for Gene Silencing
por: Aubets, Eva, et al.
Publicado: (2021)

GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling
por: Wang, Liang, et al.
Publicado: (2022)

Protein Kinase A in Human Retina: Differential Localization of Cβ, Cα, RIIα, and RIIβ in Photoreceptors Highlights Non-redundancy of Protein Kinase A Subunits
por: Roa, Jinae N., et al.
Publicado: (2021)

WNT2-Mediated FZD2 Stabilization Regulates Esophageal Cancer Metastasis via STAT3 Signaling
por: Fu, Yufei, et al.
Publicado: (2020)

Crosstalk between the p38 and TGF-β signaling pathways through TβRI, TβRII and Smad3 expression in plancental choriocarcinoma JEG-3 cells
por: TAN, YUSI, et al.
Publicado: (2014)

Downregulation of Frizzled-7 induces the apoptosis of hepatocellular carcinoma cells through inhibition of NF-κB
por: Xue, Yuyang, et al.
Publicado: (2018)

Decrease of FZD4 exon 1 methylation in probands from FZD4-associated FEVR family of phenotypic heterogeneity
por: Liu, Miaomiao, et al.
Publicado: (2022)

TGF-β2 induces Grb2 to recruit PI3-K to TGF-RII that activates JNK/AP-1-signaling and augments invasiveness of Theileria-transformed macrophages
por: Haidar, Malak, et al.
Publicado: (2015)

Dual targeting of TGF-β and PD-L1 via a bifunctional anti-PD-L1/TGF-βRII agent: status of preclinical and clinical advances
por: Lind, Hanne, et al.
Publicado: (2020)

FZD7: A potential biomarker for endometriosis
por: Lan, Suwei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_n2igmr8b9abgk9qr5t5jk5do73