Cargando…

20(S)-Protopanaxadiol saponins inhibit SKOV3 cell migration

While the anti-tumor actions of ginsenosides from Panax notoginseng are well-studied, the anti-proliferative activity of 20(S)-protopanaxadiol saponins (PDS) in Sanchi ginseng on human ovarian cancer has not been reported, nor has its effect on migration of SKOV3 cells been investigated. In the pres...

Descripción completa

Detalles Bibliográficos
Autores principales:	LI, BIN, CHEN, DAOMEI, LI, WANYI, XIAO, DAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774486/ https://www.ncbi.nlm.nih.gov/pubmed/26998063 http://dx.doi.org/10.3892/ol.2016.4155

Ejemplares similares

Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways
por: GAO, JIAN-LI, et al.
Publicado: (2013)

Prevention Effect of Protopanaxadiol-Type Saponins Saponins and Protopanaxatriol-Type Saponins on Myelosuppression Mice Induced by Cyclophosphamide
por: Zhang, He, et al.
Publicado: (2022)

Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways
por: Ren, Guoqing, et al.
Publicado: (2023)

Molecular mechanism of protopanaxadiol saponin fraction-mediated anti-inflammatory actions
por: Yang, Yanyan, et al.
Publicado: (2014)

20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient Mice
por: Liu, Conghui, et al.
Publicado: (2019)

In Vitro Transformation of Protopanaxadiol Saponins in Human Intestinal Flora and Its Effect on Intestinal Flora
por: Zhang, Meiyu, et al.
Publicado: (2021)

Saponin Fractions from Eryngium planum L. Induce Apoptosis in Ovarian SKOV-3 Cancer Cells
por: Kikowska, Małgorzata, et al.
Publicado: (2023)

Protective effect of Panax quinquefolium 20(S)-protopanaxadiol saponins, isolated from Pana quinquefolium, on permanent focal cerebral ischemic injury in rats
por: XU, HUALI, et al.
Publicado: (2014)

20(S)-Protopanaxadiol Inhibition of Progression and Growth of Castration-Resistant Prostate Cancer
por: Cao, Bo, et al.
Publicado: (2014)

Integrated Chemical and Transcriptomic Analysis Reveals the Distribution of Protopanaxadiol- and Protopanaxatriol-Type Saponins in Panax notoginseng
por: Wei, Guangfei, et al.
Publicado: (2018)

Alpha-Hederin, the Active Saponin of Nigella sativa, as an Anticancer Agent Inducing Apoptosis in the SKOV-3 Cell Line
por: Adamska, Anna, et al.
Publicado: (2019)

Computational and experimental characterization of estrogenic activities of 20(S, R)-protopanaxadiol and 20(S, R)-protopanaxatriol
por: Zhang, Tiehua, et al.
Publicado: (2020)

Synergistic production of 20(S)-protopanaxadiol from protopanaxadiol-type ginsenosides by β-glycosidases from Dictyoglomus turgidum and Caldicellulosiruptor bescii
por: Choi, Ji-Hyeon, et al.
Publicado: (2017)

Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu(2)O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton
por: Chen, Daomei, et al.
Publicado: (2021)

20(S)-protopanaxadiol promotes the migration, proliferation, and differentiation of neural stem cells by targeting GSK-3β in the Wnt/GSK-3β/β-catenin pathway
por: Lin, Kaili, et al.
Publicado: (2020)

TPX2 silencing mediated by joint action of microvesicles and ultrasonic radiation inhibits the migration and invasion of SKOV3 cells
por: Huang, Dong, et al.
Publicado: (2018)

Polycaprolactone nanofibres loaded with 20(S)-protopanaxadiol for in vitro and in vivo anti-tumour activity study
por: Liu, Dan-qing, et al.
Publicado: (2018)

Modification of ginsenoside saponin composition via the CRISPR/Cas9-mediated knockout of protopanaxadiol 6-hydroxylase gene in Panax ginseng
por: Choi, Han Suk, et al.
Publicado: (2022)

20(S)-Protopanaxadiol-Induced Apoptosis in MCF-7 Breast Cancer Cell Line through the Inhibition of PI3K/AKT/mTOR Signaling Pathway
por: Zhang, Hong, et al.
Publicado: (2018)

Ginsenoside 20(S)-protopanaxadiol induces cell death in human endometrial cancer cells via apoptosis
por: Jo, Hantae, et al.
Publicado: (2021)

20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1
por: Wang, Yuchen, et al.
Publicado: (2019)

Stereoselective Property of 20(S)-Protopanaxadiol Ocotillol Type Epimers Affects Its Absorption and Also the Inhibition of P-Glycoprotein
por: Wang, Wenyan, et al.
Publicado: (2014)

Effect of targeted silencing of IL-8 on in vitro migration and invasion of SKOV3 ovarian cancer cells
por: Li, Yanyu, et al.
Publicado: (2017)

Peptide P7 inhibits the bFGF-stimulated proliferation and invasion of SKOV3 cells
por: Chen, Qiong, et al.
Publicado: (2019)

Inhibition of Proliferation, Migration, and Invasion by Knockdown of Pyruvate Kinase-M2 (PKM2) in Ovarian Cancer SKOV3 and OVCAR3 Cells
por: Miao, Yi, et al.
Publicado: (2016)

hERG1 is involved in the pathophysiological process and inhibited by berberine in SKOV3 cells
por: Zhi, Duo, et al.
Publicado: (2019)

Protopanaxadiol inhibits epithelial–mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway
por: Yang, Lan, et al.
Publicado: (2019)

Enhanced oral absorption of 20(S)-protopanaxadiol by self-assembled liquid crystalline nanoparticles containing piperine: in vitro and in vivo studies
por: Jin, Xin, et al.
Publicado: (2013)

1α,25(OH)(2)D(3) Suppresses the Migration of Ovarian Cancer SKOV-3 Cells through the Inhibition of Epithelial–Mesenchymal Transition
por: Hou, Yong-Feng, et al.
Publicado: (2016)

Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol
por: Zhang, Qi, et al.
Publicado: (2017)

Anticancer Activities of Protopanaxadiol- and Protopanaxatriol-Type Ginsenosides and Their Metabolites
por: Chen, Xiao-Jia, et al.
Publicado: (2016)

20(S)‐Protopanaxadiol inhibits epithelial‐mesenchymal transition by promoting retinoid X receptor alpha in human colorectal carcinoma cells
por: Lu, Zeyuan, et al.
Publicado: (2020)

The anti-tumor efficacy of 20(S)-protopanaxadiol, an active metabolite of ginseng, according to fasting on hepatocellular carcinoma
por: Li, Wenzhen, et al.
Publicado: (2022)

A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ
por: Chen, Lin, et al.
Publicado: (2022)

Molecular Insight into Stereoselective ADME Characteristics of C20-24 Epimeric Epoxides of Protopanaxadiol by Docking Analysis
por: Guo, Wenna, et al.
Publicado: (2020)

Neuroprotective effects of 20(S)-protopanaxadiol against glutamate-induced mitochondrial dysfunction in PC12 cells
por: BAK, DONG-HO, et al.
Publicado: (2016)

Raptor mediates the antiproliferation of cardamonin by mTORC1 inhibition in SKOV3 cells
por: Shi, Daohua, et al.
Publicado: (2018)

Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction
por: Chen, Feiyan, et al.
Publicado: (2023)

Beneficial effects of 20(S)-protopanaxadiol on antitumor activity and toxicity of cyclophosphamide in tumor-bearing mice
por: LIN, GUANGZHU, et al.
Publicado: (2013)

20-O-β-d-Xylopyranosyl(1→6)-β-d-glucopyranosyl-20(S)-protopanaxadiol methanol solvate
por: Li, Xing-Wei, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_d5qa9qlplnf5l84agv8ddff2go