Cargando…

Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes

We examined whether apigenin affects the gene expression, secretion and activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the knee joint of rat to evaluate the potential chondroprotective effects of apigenin. R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Jin Sung, Kim, Dong Kyu, Shin, Hyun-Dae, Lee, Hyun Jae, Jo, Ho Seung, Jeong, Jin Hoon, Choi, Young Lac, Lee, Choong Jae, Hwang, Sun-Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774497/ https://www.ncbi.nlm.nih.gov/pubmed/26902085 http://dx.doi.org/10.4062/biomolther.2015.217

Ejemplares similares

Betulin suppressed interleukin-1β-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat
por: Ra, Ho Jong, et al.
Publicado: (2017)

Erratum to: Betulin suppressed interleukin-1b-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat
por: Ra, Ho Jong, et al.
Publicado: (2017)

Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo
por: Kang, Dong-Geun, et al.
Publicado: (2017)

Inhibition of the Expression of Matrix Metalloproteinases in Articular Chondrocytes by Resveratrol through Affecting Nuclear Factor-Kappa B Signaling Pathway
por: Kang, Dong-Geun, et al.
Publicado: (2018)

Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β
por: Baker, Joseph F., et al.
Publicado: (2012)

Luteolin Inhibits the Activity, Secretion and Gene Expression of MMP-3 in Cultured Articular Chondrocytes and Production of MMP-3 in the Rat Knee
por: Kang, Bun-Jung, et al.
Publicado: (2014)

Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytes
por: Liacini, Abdelhamid, et al.
Publicado: (2005)

Isoliquiritigenin Inhibits IL-1β-Induced Production of Matrix Metalloproteinase in Articular Chondrocytes
por: Zhang, Lei, et al.
Publicado: (2018)

PEP-1-FK506BP12 inhibits matrix metalloproteinase expression in human articular chondrocytes and in a mouse carrageenan-induced arthritis model
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Naringenin regulates production of matrix metalloproteinases in the knee-joint and primary cultured articular chondrocytes and alleviates pain in rat osteoarthritis model
por: Wang, C.C., et al.
Publicado: (2017)

The Role of Cyclooxygenase-2, Interleukin-1β and Fibroblast Growth Factor-2 in the Activation of Matrix Metalloproteinase-1 in Sheared-Chondrocytes and Articular Cartilage
por: Guan, Pei-Pei, et al.
Publicado: (2015)

Zinc Protects Articular Chondrocytes through Changes in Nrf2-Mediated Antioxidants, Cytokines and Matrix Metalloproteinases
por: Huang, Tzu-Ching, et al.
Publicado: (2018)

Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13
por: Long, David, et al.
Publicado: (2008)

Integrins and chondrocyte–matrix interactions in articular cartilage
por: Loeser, Richard F.
Publicado: (2014)

Fibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Gel-type autologous chondrocyte (Chondron™) implantation for treatment of articular cartilage defects of the knee
por: Choi, Nam-Yong, et al.
Publicado: (2010)

Production of interleukin-1 receptor antagonist by human articular chondrocytes
por: Palmer, Gaby, et al.
Publicado: (2002)

Rosmarinic acid induces rabbit articular chondrocyte differentiation by decreases matrix metalloproteinase-13 and inflammation by upregulating cyclooxygenase-2 expression
por: Eo, Seong-Hui, et al.
Publicado: (2017)

Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators
por: Choi, Hyun-Mi, et al.
Publicado: (2009)

Matrix Metalloproteinase-9 Production by Immortalized Human Chondrocyte Lines
por: Malemud, Charles J., et al.
Publicado: (2016)

Differential regulation of the water channel protein aquaporins in chondrocytes of human knee articular cartilage by aging
por: Kyung, Bong Soo, et al.
Publicado: (2021)

Production of interleukin (IL)-1 receptor antagonist by human articular chondrocytes
por: Palmer, G, et al.
Publicado: (2002)

The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes
por: Elliott, Sarah, et al.
Publicado: (2003)

Apigenin Inhibits Tumor Necrosis Factor-α-Induced Production and Gene Expression of Mucin through Regulating Nuclear Factor-Kappa B Signaling Pathway in Airway Epithelial Cells
por: Seo, Hyo-Seok, et al.
Publicado: (2014)

Interleukin-33, matrix metalloproteinase-9, and tissue ınhibitor of matrix metalloproteinase-1 in myocardial infarction
por: Guzel, Savas, et al.
Publicado: (2013)

Interplay between Matrix Metalloproteinase-9, Matrix Metalloproteinase-2, and Interleukins in Multiple Sclerosis Patients
por: Trentini, Alessandro, et al.
Publicado: (2016)

The Effect of Imiquimod on Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Malignant Melanoma Cell Invasion
por: Jung, Jin Young, et al.
Publicado: (2014)

Disturbed Matrix Metalloproteinase Pathway in Both Age-Related Macular Degeneration and Alzheimer's Disease
por: Hussain, Ali Aijaz, et al.
Publicado: (2017)

Modulation of Apoptosis and Differentiation by the Treatment of Sulfasalazine in Rabbit Articular Chondrocytes
por: Lee, Won Kil, et al.
Publicado: (2016)

Effects of gangliosides from deer bone extract on the gene expressions of matrix metalloproteinases and collagen type II in interleukin-1β-induced osteoarthritic chondrocytes
por: Suh, Hyung Joo, et al.
Publicado: (2016)

Integrin-regulated Secretion of Interleukin 4: A Novel Pathway of Mechanotransduction in Human Articular Chondrocytes
por: Millward-Sadler, S.J., et al.
Publicado: (1999)

Mitosis of Chondrocytes Induced in the Knee Joint Articular Cartilage of Adult Rabbits
por: Crelin, E. S., et al.
Publicado: (1960)

Effects of chondrocyte-derived extracellular matrix in a dry eye mouse model
por: Kim, Chae Eun, et al.
Publicado: (2015)

Comparison of MRI T2 Relaxation Changes of Knee Articular Cartilage before and after Running between Young and Old Amateur Athletes
por: Cha, Jang Gyu, et al.
Publicado: (2012)

Erratum: Interleukin-33, matrix metalloproteinase-9, and tissue inhibitor of matrix metalloproteinase-1 in myocardial infarction
por: Guzel, Savas, et al.
Publicado: (2013)

The Role of Membrane-Type 1 Matrix Metalloproteinase–Substrate Interactions in Pathogenesis
por: Lee, Hyun, et al.
Publicado: (2023)

Matrix Metalloproteinases and Glaucoma
por: Kim, Moo Hyun, et al.
Publicado: (2022)

Anti-osteoarthritic Effects of an Herbal Composition LI73014F2 on Interleukin-1β-induced Primary Human Articular Chondrocytes
por: Kim, Hae Lim, et al.
Publicado: (2020)

Pravastatin Reduces Matrix Metalloproteinases Expression and Promotes Cholesterol Efflux in Osteoarthritis Chondrocytes
por: Wu, Yunpeng, et al.
Publicado: (2022)

Apigenin and Wogonin Regulate Epidermal Growth Factor Receptor Signaling Pathway Involved in MUC5AC Mucin Gene Expression and Production from Cultured Airway Epithelial Cells
por: Sikder, Md. Asaduzzaman, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_uu3ln3gu7c5hr89lpol48p8m3r