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Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes

AIM: The present study was undertaken to ascertain the clinical observation and haemato-biochemical studies on fever of unknown origin (FUO) in buffaloes which were presented for treatment at the Teaching Veterinary Clinical Complex (TVCC), Lala Lajpat Rai University of Veterinary and Animal Science...

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Autores principales: Kumar, Parmod, Jain, V. K., Kumar, Ankit, Sindhu, Neelesh, Kumar, Tarun, Charaya, Gaurav, Surbhi, Kumar, Sandeep, Agnihotri, Divya, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774660/
https://www.ncbi.nlm.nih.gov/pubmed/27047022
http://dx.doi.org/10.14202/vetworld.2015.1225-1229
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author Kumar, Parmod
Jain, V. K.
Kumar, Ankit
Sindhu, Neelesh
Kumar, Tarun
Charaya, Gaurav
Surbhi,
Kumar, Sandeep
Agnihotri, Divya
Sridhar,
author_facet Kumar, Parmod
Jain, V. K.
Kumar, Ankit
Sindhu, Neelesh
Kumar, Tarun
Charaya, Gaurav
Surbhi,
Kumar, Sandeep
Agnihotri, Divya
Sridhar,
author_sort Kumar, Parmod
collection PubMed
description AIM: The present study was undertaken to ascertain the clinical observation and haemato-biochemical studies on fever of unknown origin (FUO) in buffaloes which were presented for treatment at the Teaching Veterinary Clinical Complex (TVCC), Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar. MATERIALS AND METHODS: The investigation was conducted on total 106 clinical cases presented at “TVCC, LUVAS, Hisar.” Diseased animals having history of fever and increased rectal temperature were considered for the current study. Diagnosis of FUO was done on the basis of negative parasitological examination, culture examination, fecal and urine test. The cases in which etiology could not be established (such as pneumonia, metritis, traumatic reticuloperitonitis, urinary tract infection, trypanosomosis, diaphragmatic hernia, Brucellosis, and foreign body) were considered as true cases of FUO. RESULTS: Out of 106 clinical cases different etiologies were identified in 76 (71.70%) cases including pneumonia, traumatic pericarditis, trypanosomosis, bacteremia, etc. and 30 cases (28.30%) remained undiagnosed even after detailed investigation. The mean rectal temperature (104.43±0.16°F), respiration rate (56.57±1.51/min) and pulse rate (83.40±1.77/min) of animals (n=30) suffering from FUO were significantly higher, whereas ruminal movement (1.00±0.23) was significantly lower compared to healthy control group. The mean value of hemoglobin, lymphocytes, and packed cell volume were significantly lower, whereas mean value of neutrophils was significantly higher compared to that of healthy control animals. Mean value of serum levels of glucose, phosphorus, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine phosphokinase (CPK), blood urea nitrogen (BUN), and creatinine were found to be significantly higher, whereas mean value of calcium value was significantly lower in all clinically affected animals compared to the healthy control group. CONCLUSION: About 28.30% cases of fever in buffaloes were found to be of unknown origin. Haemato-biochemical findings in cases of FUO in buffaloes revealed relative neutrophilia with lymphopenia, hyperglycemia, hypocalcemia, hyperphosphatemia, significantly increased AST, ALT, and CPK along with adversely altered kidney function indicators (elevated BUN and serum creatinine).
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spelling pubmed-47746602016-04-04 Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes Kumar, Parmod Jain, V. K. Kumar, Ankit Sindhu, Neelesh Kumar, Tarun Charaya, Gaurav Surbhi, Kumar, Sandeep Agnihotri, Divya Sridhar, Vet World Research Article AIM: The present study was undertaken to ascertain the clinical observation and haemato-biochemical studies on fever of unknown origin (FUO) in buffaloes which were presented for treatment at the Teaching Veterinary Clinical Complex (TVCC), Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar. MATERIALS AND METHODS: The investigation was conducted on total 106 clinical cases presented at “TVCC, LUVAS, Hisar.” Diseased animals having history of fever and increased rectal temperature were considered for the current study. Diagnosis of FUO was done on the basis of negative parasitological examination, culture examination, fecal and urine test. The cases in which etiology could not be established (such as pneumonia, metritis, traumatic reticuloperitonitis, urinary tract infection, trypanosomosis, diaphragmatic hernia, Brucellosis, and foreign body) were considered as true cases of FUO. RESULTS: Out of 106 clinical cases different etiologies were identified in 76 (71.70%) cases including pneumonia, traumatic pericarditis, trypanosomosis, bacteremia, etc. and 30 cases (28.30%) remained undiagnosed even after detailed investigation. The mean rectal temperature (104.43±0.16°F), respiration rate (56.57±1.51/min) and pulse rate (83.40±1.77/min) of animals (n=30) suffering from FUO were significantly higher, whereas ruminal movement (1.00±0.23) was significantly lower compared to healthy control group. The mean value of hemoglobin, lymphocytes, and packed cell volume were significantly lower, whereas mean value of neutrophils was significantly higher compared to that of healthy control animals. Mean value of serum levels of glucose, phosphorus, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine phosphokinase (CPK), blood urea nitrogen (BUN), and creatinine were found to be significantly higher, whereas mean value of calcium value was significantly lower in all clinically affected animals compared to the healthy control group. CONCLUSION: About 28.30% cases of fever in buffaloes were found to be of unknown origin. Haemato-biochemical findings in cases of FUO in buffaloes revealed relative neutrophilia with lymphopenia, hyperglycemia, hypocalcemia, hyperphosphatemia, significantly increased AST, ALT, and CPK along with adversely altered kidney function indicators (elevated BUN and serum creatinine). Veterinary World 2015-10 2015-10-23 /pmc/articles/PMC4774660/ /pubmed/27047022 http://dx.doi.org/10.14202/vetworld.2015.1225-1229 Text en Copyright: The authors. http://creativecommons.org/licenses/by/2.0 This article is an open access article licensed under the terms of the Creative Commons Attributin License (http://creative commons.org/licenses/by/2.0) which permits unrestricted use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Research Article
Kumar, Parmod
Jain, V. K.
Kumar, Ankit
Sindhu, Neelesh
Kumar, Tarun
Charaya, Gaurav
Surbhi,
Kumar, Sandeep
Agnihotri, Divya
Sridhar,
Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes
title Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes
title_full Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes
title_fullStr Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes
title_full_unstemmed Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes
title_short Clinical and hemato-biochemical studies on fever of unknown origin in buffaloes
title_sort clinical and hemato-biochemical studies on fever of unknown origin in buffaloes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774660/
https://www.ncbi.nlm.nih.gov/pubmed/27047022
http://dx.doi.org/10.14202/vetworld.2015.1225-1229
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