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EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis

BACKGROUND: EspP (E. coli secreted serine protease, large plasmid encoded) is an extracellular serine protease produced by enterohemorrhagic E. coli (EHEC) O157:H7, a causative agent of diarrhea-associated Hemolytic Uremic Syndrome (D+HUS). The mechanism by which EHEC induces D+HUS has not been full...

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Detalles Bibliográficos
Autores principales:	Kuo, Kevin H. M., Khan, Shekeb, Rand, Margaret L., Mian, Hira S., Brnjac, Elena, Sandercock, Linda E., Akula, Indira, Julien, Jean-Philippe, Pai, Emil F., Chesney, Alden E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775034/ https://www.ncbi.nlm.nih.gov/pubmed/26934472 http://dx.doi.org/10.1371/journal.pone.0149830

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