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Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove

HLA class I presentation of pathogen-derived peptide ligands is essential for CD8+ T-cell recognition of Toxoplasma gondii infected cells. Currently, little data exist pertaining to peptides that are presented after T. gondii infection. Herein we purify HLA-A*02:01 complexes from T. gondii infected...

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Detalles Bibliográficos
Autores principales: McMurtrey, Curtis, Trolle, Thomas, Sansom, Tiffany, Remesh, Soumya G, Kaever, Thomas, Bardet, Wilfried, Jackson, Kenneth, McLeod, Rima, Sette, Alessandro, Nielsen, Morten, Zajonc, Dirk M, Blader, Ira J, Peters, Bjoern, Hildebrand, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775218/
https://www.ncbi.nlm.nih.gov/pubmed/26824387
http://dx.doi.org/10.7554/eLife.12556