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Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1

The heat shock response is a universal homeostatic cell autonomous reaction of organisms to cope with adverse environmental conditions. In mammalian cells, this response is mediated by the heat shock transcription factor Hsf1, which is monomeric in unstressed cells and upon activation trimerizes, an...

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Detalles Bibliográficos
Autores principales:	Hentze, Nikolai, Le Breton, Laura, Wiesner, Jan, Kempf, Georg, Mayer, Matthias P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775227/ https://www.ncbi.nlm.nih.gov/pubmed/26785146 http://dx.doi.org/10.7554/eLife.11576

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