Interactive analysis and assessment of single-cell copy-number variations

We present an open-source web platform, Ginkgo (http://qb.cshl.edu/ginkgo), for the analysis and assessment of single-cell copy-number variations (CNVs). Ginkgo automatically constructs copy-number profiles of cells from mapped reads and constructs phylogenetic trees of related cells. We validate Gi...

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Detalles Bibliográficos
Autores principales: Garvin, Tyler, Aboukhalil, Robert, Kendall, Jude, Baslan, Timour, Atwal, Gurinder S., Hicks, James, Wigler, Michael, Schatz, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775251/
https://www.ncbi.nlm.nih.gov/pubmed/26344043
http://dx.doi.org/10.1038/nmeth.3578

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