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Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides
Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-ol...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775785/ https://www.ncbi.nlm.nih.gov/pubmed/26989539 http://dx.doi.org/10.1155/2016/4786498 |
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author | Aldrees, Sultan S. Zoroquiain, Pablo Alghamdi, Sarah A. Logan, Patrick T. Callejo, Sonia Burnier, Miguel N. |
author_facet | Aldrees, Sultan S. Zoroquiain, Pablo Alghamdi, Sarah A. Logan, Patrick T. Callejo, Sonia Burnier, Miguel N. |
author_sort | Aldrees, Sultan S. |
collection | PubMed |
description | Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-old man who was previously diagnosed with MF in 2010 and was treated presented in 2014 complaining of foreign body sensation and redness in both eyes. Slit lamp examination of both eyes showed erythematous conjunctival growth that extended circumferentially. Physical examination revealed erythematous skin lesions on different body parts. Conjunctival biopsy was performed and revealed a dense, highly polymorphic lymphocytic population. The immunophenotype demonstrated a neoplastic T-cell origin consistent with MF. A diagnosis of conjunctival involvement by MF was made. The conjunctiva was treated with radiotherapy resulting in tumor regression. There were no recurrences at the 6-month follow-up. Conclusion. T-cell lymphoma should be considered in patients with a history of MF presenting with conjunctival and skin lesions. |
format | Online Article Text |
id | pubmed-4775785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-47757852016-03-17 Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides Aldrees, Sultan S. Zoroquiain, Pablo Alghamdi, Sarah A. Logan, Patrick T. Callejo, Sonia Burnier, Miguel N. Case Rep Ophthalmol Med Case Report Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-old man who was previously diagnosed with MF in 2010 and was treated presented in 2014 complaining of foreign body sensation and redness in both eyes. Slit lamp examination of both eyes showed erythematous conjunctival growth that extended circumferentially. Physical examination revealed erythematous skin lesions on different body parts. Conjunctival biopsy was performed and revealed a dense, highly polymorphic lymphocytic population. The immunophenotype demonstrated a neoplastic T-cell origin consistent with MF. A diagnosis of conjunctival involvement by MF was made. The conjunctiva was treated with radiotherapy resulting in tumor regression. There were no recurrences at the 6-month follow-up. Conclusion. T-cell lymphoma should be considered in patients with a history of MF presenting with conjunctival and skin lesions. Hindawi Publishing Corporation 2016 2016-02-18 /pmc/articles/PMC4775785/ /pubmed/26989539 http://dx.doi.org/10.1155/2016/4786498 Text en Copyright © 2016 Sultan S. Aldrees et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Aldrees, Sultan S. Zoroquiain, Pablo Alghamdi, Sarah A. Logan, Patrick T. Callejo, Sonia Burnier, Miguel N. Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides |
title | Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides |
title_full | Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides |
title_fullStr | Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides |
title_full_unstemmed | Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides |
title_short | Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides |
title_sort | conjunctival involvement of t-cell lymphoma in a patient with mycosis fungoides |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775785/ https://www.ncbi.nlm.nih.gov/pubmed/26989539 http://dx.doi.org/10.1155/2016/4786498 |
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