Cargando…

Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides

Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-ol...

Descripción completa

Detalles Bibliográficos
Autores principales: Aldrees, Sultan S., Zoroquiain, Pablo, Alghamdi, Sarah A., Logan, Patrick T., Callejo, Sonia, Burnier, Miguel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775785/
https://www.ncbi.nlm.nih.gov/pubmed/26989539
http://dx.doi.org/10.1155/2016/4786498
_version_ 1782419058138808320
author Aldrees, Sultan S.
Zoroquiain, Pablo
Alghamdi, Sarah A.
Logan, Patrick T.
Callejo, Sonia
Burnier, Miguel N.
author_facet Aldrees, Sultan S.
Zoroquiain, Pablo
Alghamdi, Sarah A.
Logan, Patrick T.
Callejo, Sonia
Burnier, Miguel N.
author_sort Aldrees, Sultan S.
collection PubMed
description Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-old man who was previously diagnosed with MF in 2010 and was treated presented in 2014 complaining of foreign body sensation and redness in both eyes. Slit lamp examination of both eyes showed erythematous conjunctival growth that extended circumferentially. Physical examination revealed erythematous skin lesions on different body parts. Conjunctival biopsy was performed and revealed a dense, highly polymorphic lymphocytic population. The immunophenotype demonstrated a neoplastic T-cell origin consistent with MF. A diagnosis of conjunctival involvement by MF was made. The conjunctiva was treated with radiotherapy resulting in tumor regression. There were no recurrences at the 6-month follow-up. Conclusion. T-cell lymphoma should be considered in patients with a history of MF presenting with conjunctival and skin lesions.
format Online
Article
Text
id pubmed-4775785
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-47757852016-03-17 Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides Aldrees, Sultan S. Zoroquiain, Pablo Alghamdi, Sarah A. Logan, Patrick T. Callejo, Sonia Burnier, Miguel N. Case Rep Ophthalmol Med Case Report Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-old man who was previously diagnosed with MF in 2010 and was treated presented in 2014 complaining of foreign body sensation and redness in both eyes. Slit lamp examination of both eyes showed erythematous conjunctival growth that extended circumferentially. Physical examination revealed erythematous skin lesions on different body parts. Conjunctival biopsy was performed and revealed a dense, highly polymorphic lymphocytic population. The immunophenotype demonstrated a neoplastic T-cell origin consistent with MF. A diagnosis of conjunctival involvement by MF was made. The conjunctiva was treated with radiotherapy resulting in tumor regression. There were no recurrences at the 6-month follow-up. Conclusion. T-cell lymphoma should be considered in patients with a history of MF presenting with conjunctival and skin lesions. Hindawi Publishing Corporation 2016 2016-02-18 /pmc/articles/PMC4775785/ /pubmed/26989539 http://dx.doi.org/10.1155/2016/4786498 Text en Copyright © 2016 Sultan S. Aldrees et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aldrees, Sultan S.
Zoroquiain, Pablo
Alghamdi, Sarah A.
Logan, Patrick T.
Callejo, Sonia
Burnier, Miguel N.
Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides
title Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides
title_full Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides
title_fullStr Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides
title_full_unstemmed Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides
title_short Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides
title_sort conjunctival involvement of t-cell lymphoma in a patient with mycosis fungoides
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775785/
https://www.ncbi.nlm.nih.gov/pubmed/26989539
http://dx.doi.org/10.1155/2016/4786498
work_keys_str_mv AT aldreessultans conjunctivalinvolvementoftcelllymphomainapatientwithmycosisfungoides
AT zoroquiainpablo conjunctivalinvolvementoftcelllymphomainapatientwithmycosisfungoides
AT alghamdisaraha conjunctivalinvolvementoftcelllymphomainapatientwithmycosisfungoides
AT loganpatrickt conjunctivalinvolvementoftcelllymphomainapatientwithmycosisfungoides
AT callejosonia conjunctivalinvolvementoftcelllymphomainapatientwithmycosisfungoides
AT burniermigueln conjunctivalinvolvementoftcelllymphomainapatientwithmycosisfungoides