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CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients
OBJECTIVE: To assess if the percentage of CD3(+)CD4(+)CD62L(+) cells in cryopreserved peripheral blood mononuclear cells (PBMCs) (here termed %CD62L) can predict risk of developing progressive multifocal leukoencephalopathy (PML) and better inform the physician for benefit–risk assessment of nataliz...
Autores principales: | Lieberman, Linda A., Zeng, Wanyong, Singh, Carol, Wang, Wenting, Otipoby, Kevin L., Loh, Christine, Plavina, Tatiana, Gorelik, Leonid, Ransohoff, Richard M., Cahir-McFarland, Ellen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776091/ https://www.ncbi.nlm.nih.gov/pubmed/26718566 http://dx.doi.org/10.1212/WNL.0000000000002314 |
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