The Lipid Bilayer Provides a Site for Cortisone Crystallization at High Cortisone Concentrations

Cortisone is an injected anti-inflammatory drug that can cause painful side effects known as “steroid flares” which are caused by cortisone crystallizing at the injection site. We used molecular dynamics simulations and X-ray diffraction to study the interaction of cortisone with model lipid membran...

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Detalles Bibliográficos
Autores principales: Alsop, Richard J., Khondker, Adree, Hub, Jochen S., Rheinstädter, Maikel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776104/
https://www.ncbi.nlm.nih.gov/pubmed/26936102
http://dx.doi.org/10.1038/srep22425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776104/
https://www.ncbi.nlm.nih.gov/pubmed/26936102
http://dx.doi.org/10.1038/srep22425

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