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The Lipid Bilayer Provides a Site for Cortisone Crystallization at High Cortisone Concentrations
Cortisone is an injected anti-inflammatory drug that can cause painful side effects known as “steroid flares” which are caused by cortisone crystallizing at the injection site. We used molecular dynamics simulations and X-ray diffraction to study the interaction of cortisone with model lipid membran...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776104/ https://www.ncbi.nlm.nih.gov/pubmed/26936102 http://dx.doi.org/10.1038/srep22425 |