Activation of innate antiviral immune response via double-stranded RNA-dependent RLR receptor-mediated necroptosis

Viruses induce double-stranded RNA (dsRNA) in the host cells. The mammalian system has developed dsRNA-dependent recognition receptors such as RLRs that recognize the long stretches of dsRNA as PAMPs to activate interferon-mediated antiviral pathways and apoptosis in severe infection. Here we report...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wang, Wei-Hua, Azadzoi, Kazem M., Su, Ning, Dai, Peng, Sun, Jianbin, Wang, Qin, Liang, Ping, Zhang, Wentao, Lei, Xiaoying, Yan, Zhen, Yang, Jing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776105/
https://www.ncbi.nlm.nih.gov/pubmed/26935990
http://dx.doi.org/10.1038/srep22550

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