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All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation

All trans retinoic acid (atRA) is one of the most potent therapeutic agents, but extensive toxicity caused by nuclear RA receptors (RARs) limits its clinical application in treating cancer. AtRA also exerts non-genomic activities for which the mechanism remains poorly understood. We determine that c...

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Detalles Bibliográficos
Autores principales:	Persaud, Shawna D., Park, Sung Wook, Ishigami-Yuasa, Mari, Koyano-Nakagawa, Naoko, Kagechika, Hiroyuki, Wei, Li-Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776112/ https://www.ncbi.nlm.nih.gov/pubmed/26935534 http://dx.doi.org/10.1038/srep22396

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