TGFβ signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells

Human urine cells (HUCs) can be reprogrammed into neural progenitor cells (NPCs) or induced pluripotent stem cells (iPSCs) with defined factors and a small molecule cocktail, but the underlying fate choice remains unresolved. Here, through sequential removal of individual compound from small molecul...

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Detalles Bibliográficos
Autores principales: Wang, Lihui, Li, Xirui, Huang, Wenhao, Zhou, Tiancheng, Wang, Haitao, Lin, Aiping, Hutchins, Andrew Paul, Su, Zhenghui, Chen, Qianyu, Pei, Duanqing, Pan, Guangjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776143/
https://www.ncbi.nlm.nih.gov/pubmed/26935433
http://dx.doi.org/10.1038/srep22484

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