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Regulation of global gene expression and cell proliferation by APP

Down syndrome (DS), caused by trisomy of chromosome 21, is one of the most common genetic disorders. Patients with DS display growth retardation and inevitably develop characteristic Alzheimer’s disease (AD) neuropathology, including neurofibrillary tangles and neuritic plaques. The expression of am...

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Detalles Bibliográficos
Autores principales:	Wu, Yili, Zhang, Si, Xu, Qin, Zou, Haiyan, Zhou, Weihui, Cai, Fang, Li, Tingyu, Song, Weihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776145/ https://www.ncbi.nlm.nih.gov/pubmed/26936520 http://dx.doi.org/10.1038/srep22460

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